Dr. Brian Weiss is a highly respected psychiatrist from the mainstream of the medical establishment. Catherine is one of his most difficult cases, a twenty-seven year old woman racked by phobias and anxieties. In the course of Catherine's treatment, Dr. Weiss makes a startling discovery. Under hypnosis, she recollects, in vivid detail, events from past lives ranging from the prehistoric times and ancient Egypt to the 20th Century and the fires of World War II. Encouraging Catherine to relive her most painful experience even her moments of death. Dr. Weiss steers her toward recovery, while his own life is dramatically changed forever. In Many Lives, Many Masters, Dr. Weiss tells the true story of Catherine her many existences, her remarkable therapy sessions, and the vision she revealed of the human mind and soul.